Visitors to the Maritime Museum of the Atlantic this weekend will have the opportunity to view model ships of all shapes and sizes. Hosted by the Maritime Ship Modeler’s Guild and featuring model makers from across Nova Scotia and New Brunswick, the weekend showcase will boast ship models as well as free model building activities for children. The showcase will also celebrate the guild’s dedication to volunteering. Since 2003, a group of modelers have donated nearly 13,000 hours worth of work to the museum, using their expertise and love of model making to conserve, treat and preserve almost all of the models in the museum’s extensive collection. From cleaning simple, wooden, recognition models, to completely restoring all 13-feet of the damaged RMS Franconia model, these volunteers have ensured that hundreds of historically important models will be exhibit ready for years to come. The showcase will take place from 10 a.m. to 5 p.m. on Saturday, April 21 and Sunday, April 22. Admission will be charged. The Maritime Museum of the Atlantic is located at 1675 Lower Water St. in Halifax.
Casablanca — King Mohammed VI is set to attend the COP22 climate change conference in Marrakech starting Monday, November 14.The sovereign was in Senegal for the past week for a friendly visit, where he delivered an historic speech commemorating the Green March and also participated in the signing of four important economic agreements.The COP22 however, which has been taking place since November 7, is also awaiting the monarch’s presence, as he is expected to attend the Africa Action Summit on November 15 and welcome leaders from various African countries. This will be an opportune moment to again convince other African leaders to support Morocco’s re-entry to the African Union. Morocco’s request to re-enter has been in the hands of Nkosazana Dlamini Zuma, head of the Union, for well over a month.The king’s presence at COP22 is important as more than 40,000 visitors from all over the world come together to try and put the Paris Agreement into concrete motion.
Rabat – Air Arabia Maroc has launched a new weekly flight connecting Rabat and Casablanca.The flights will began yesterday and will continue until March 26. The 20-minute flights will operate on the Airbus A320, which has 168 seats.Departing flights from Rabat will leave at 8:15 a.m. Departing flights from Casablanca are scheduled for 8:35 p.m. In October 2018, Air Arabia launched flights from Tangier to four other Moroccan cities: Agadir, Marrakech, Fez, Nador.Read Also: Air Arabia Maroc Launches 3 Domestic Flights from AgadirHeadquartered in Casablanca, Air Arabia Maroc is a member of the Air Arabia group. The low-cost carrier launched in Morocco in April 2009. Air Arabia Maroc also provides low-cost flights connecting Moroccan cities with international destinations. The airline serves more than 30 destinations. Air Arabia Maroc runs flights out of Casablanca, Tangier, Fez, Nador, and Agadir to various European cities.
LONDON — Discount airline easyJet warned Monday that the U.K.’s pending withdrawal from the European Union is causing travellers to hold back on booking tickets amid doubts over what Britain’s future relations with the bloc will be.EasyJet said that as a result, its earnings would be weaker in the second half of the year. Its first half loss of 275 million pounds ($360 million) was within expectations, but the outlook for the six months through September is “more cautious.”“For the second half we are seeing softness in both the U.K. and Europe, which we believe comes from macroeconomic uncertainty and many unanswered questions surrounding Brexit which are together driving weaker customer demand,” easyJet CEO Johan Lundgren said. “We are rolling out further initiatives to support our trading.”Shares in the company fell almost 9 per cent in London on the news. Shares in other airlines and travel companies also fell, with British Airways owner IAG down about 2 per cent and travel group TUI down 3 per cent.George Salmon, an analyst at Hargreaves Lansdown, said the airline is facing issues with “two main moving parts,” — namely fuel prices and customer sentiment. He said higher fuel costs are hitting profits and Britain’s pending EU divorce is making customers think twice before booking trips away.“The group reckons demand will pick up later in the year, but a more pragmatic observer would say it’s difficult to put a timeframe on when (the U.K. government) and the EU will solve the Brexit puzzle,” he said. “This uncertainty means easyJet requires some blue sky thinking just now.”Danica Kirka, The Associated Press
30 April 2007International judges at the United Nations-backed trials of former Khmer Rouge leaders, accused of mass killings and other horrific crimes during the late 1970s, today welcomed Cambodia’s decision to reduce fees for international lawyers, saying it opened the way for the court to move quickly to start its work. International judges at the United Nations-backed trials of former Khmer Rouge leaders, accused of mass killings and other horrific crimes during the late 1970s, today welcomed Cambodia’s decision to reduce fees for international lawyers, saying it opened the way for the court to move quickly to start its work. The judges of the Extraordinary Chambers in the Courts of Cambodia said they were pleased to learn of a recent decision by the Cambodian Bar Council to institute a flatregistration fee of $500 for all international lawyers appearing before the court. This is down from a $4,900 fee for foreign lawyers, an amount the international judges warned earlier this month was prohibitive and went against all international practice. “With this decision, the international judges believe that a successful plenary can now becalled to adopt the internal rules of the Extraordinary Chambers. It is expected that thisplenary will be held in the last week of May 2007,” the international judges said in a statement released in Phnom Penh. “The international judges express their hope that Extraordinary Chambers can move forward without further delay, so as to discharge its historic responsibility to find justice for the Cambodian people.” This fee dispute was the latest delay in the long-awaited trials, judges and prosecutors for which were sworn in last July. Under an agreement signed by the UN and Cambodia, the trial court and a Supreme Court within the Cambodian legal system will investigate those most responsible for crimes and serious violations of Cambodian and international law between 17 April 1975 and 6 January 1979. The UN will pay $43 million of the $56.3 million budget for the trials, with the Cambodian Government providing $13.3 million.
As Canadians head through tax filing season, professionals say missed deductions and a fear of making mistakes are among the biggest obstacles for many people.Tax software removes mistakes in arithmetic, but people need to be aware of how any changes in their lives will affect their taxes, said tax guru Evelyn Jacks.“The errors of omission are going to come from you,” said Ms. Jacks, who has written more than 45 books on taxes and wealth management.She said the goal should be to pay the least tax allowed by law.“What you want to strive to do is pay the correct amount of tax and no more.”But Canadians commonly fail to make all their eligible claims for medical expenses as well as moving expenses such as such as real estate commissions, Ms. Jacks said from Winnipeg.“People just don’t know what’s claimable,” she added.Examples of claimable expenses include: the cost of widening a doorway to accommodate someone in a wheel chair, hearing aids and hearing aid batteries.“People don’t understand that they can adjust their tax returns if they miss something and you can basically go back 10 years on most federal provisions.So if you become aware of something, maybe a pro can help you recover taxes from the past.”As for tech savvy young people born between 1980 and 1995, the survey found that only about a third planned to do their own taxes using software while 26% said they would go to a professional accountant.“We know that they’re very comfortable using technology, but for some reason the issue is really a misperception that filing your taxes using software is somehow difficult or scary,” said Ms. Rayani, who’s based in Edmonton.How to deal with investment income can also be challenging for Canadians. “While many Canadians are familiar with the basics of tax preparation, there appears to be a knowledge gap particularly on investment income,” said John Waters, head of tax and estate planning at BMO Nesbitt Burns.A study by BMO Nesbitt Burns found that 58% of Canadians weren’t sure about how capital gains are taxed and 33% lacked knowledge on how charitable donations are taxed.Ms. Jacks said Canadians also need to be aware of the family caregiver tax credit if applicable and changes to the Canada Pension Plan and Old Age Security.Beginning in 2023, the federal government is gradually shifting the age of eligibility for old age security and guaranteed income supplement payments from 65 to 67.“You really need to inform yourself so that you can set up your affairs to benefit from the tax system.”Most tax software packages optimize expenses that can be transferred between family members, Ms. Jacks said.“The family economic unit is going to do better when you file your tax returns together because we can transfer things back and forth.”Ms. Jacks noted that the average tax refund for 2011 was just under $1,700.“A refund is not necessarily a good thing because that’s just the money you have overpaid.”The deadline for filing 2012 income tax returns without late penalties is April 30.—According to tax experts, these are five common problems that can cause mistakes when people file their tax returns:1. Miss deductions such as medical, transit pass and caregiver credits.2. Lose or misplace receipts.3. Unaware of changes to tax laws.4. Don’t understand how investments are taxed.5. Don’t understand how to transfer tuition or medical expenses between family members.
by The Canadian Press Posted Apr 17, 2013 5:40 pm MDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email Most actively traded companies on the TSX, TSX Venture Exchange markets TORONTO – Some of the most active companies traded Wednesday on the Toronto Stock Exchange and the TSX Venture Exchange:Toronto Stock Exchange (11,947.29 down 172.64 points):Alterra Power Corp. (TSX:AXY). Renewable power producer. Up 1.5 cents, or five per cent, at 31.5 cents on 15.4 million shares.Osisko Mining Corp. (TSX:OSK). Miner. Down 47 cents, or 11.87 per cent, at $3.49 on 10.8 million shares. The stock continued its decline since last week as gold stocks lost their lustre on weak bullion prices. The June gold contract finished US$4.70 lower at $1,382.70 an ounce on the New York Mercantile Exchange.Barrick Gold Corp. (TSX:ABX). Miner. Down $1.07, or 5.56 per cent, at $18.17 on 10.41 million shares. Moody’s Investors Service said it is reviewing a possible downgrade of the giant gold miner’s rating after a Chilean court last week halted construction at its $8 billion Pascua-Lama project due to environmental concerns.INV Metals Inc. (TSX:INV). Miner. Unchanged at 2.5 cents on 8.44 million shares.First Quantum Minerals Ltd. (TSX:FM). Miner. Down $1.60, or 9.40 per cent, at $15.43 on 6.28 million shares.Bombardier Inc. (TSX:BBD.B). Transportation equipment. Down seven cents, or 1.77 per cent, at $3.88 on 5.83 million shares.Toronto Venture Exchange (921.70 down 38.30 points):Sandstorm Metals and Energy Ltd. (TSXV:SND). Down two cents, or 6.25 per cent, at 30 cents on 5.04 million shares.Ultra Lithim Inc. (TSXV:ULI). Up 1.5 cents, or 17.65 per cent, at 10 cents on 3.64 million shares.Companies reporting major news:Rogers Communications (TSX:RCI.B). Media and communications. Down 56 cents, or 1.08 per cent, at $51.39 on 885,342 shares. The company bought Blackiron Data from Primus Telecommunications Group for $200 million in cash. The data centre and cloud computing company’s 132 employees will join Rogers.SNC-Lavalin Group Inc. (TSX:SNC). Engineering and construction. Down 87 cents, or 2.05 per cent, at $1.63 on 1.58 million shares. The company, which is grappling with a number of controversies, reached a settlement with the World Bank Group in an investigation into allegations of bribery involving a bridge contract in Bangladesh. No financial penalty was imposed.
Let us know what you like about Geek by taking our survey. When it comes to huge and awesome things in video games, you can’t go wrong the BFG, the iconic weapon and naughty acronym from the seminal PC first-person shooter Doom. Technically the Nvidia BFGD, the new monitor revealed at CES 2018, stands for “Big Format Gaming Display.” But when it comes to this huge and awesome 65-inch gaming monitor, the reference is clear.Although many gamers love to relax and play on expansive televisions, there’s a reason why you go with relatively small monitors when you’re looking for speedy performance and crisp video quality. The Nvidia BFGD looks to combine the benefits of those monitors on a TV-sized screen. Nvidia’s G-Sync tech and impressive a native 120Hz refresh rate aim to keep the image smooth and responsive without tearing or artifacting. The right Nvidia card inside your PC itself should keep input latency low when connected to the monitor.The 65-inch backlit LED screen sports a 4K resolution as well as HDR, or High-Dynamic Range, video. So PlayStation 4 Pro and Xbox One X owners may want to give the BFGD a look as well. Finally, you’ll be able to count the individual feathers in the bird from Assassin’s Creed Origins or shoot guns in PlayerUnknown’s Battlegrounds with eSports-level accuracy.However, just because the BFGD is the size of a TV doesn’t mean it acts like one. It’s a monitor, so there’s no TV tuner or support for antenna broadcasts. But the built-in Nvidia Shield Android streaming media device does replicate much of that TV functionality. Using the remote, controller, or Google Assistant voice commands BFGD owners can access all the apps available on the Nvidia Shield from games like Crossy Road to media servers like Plex to streaming TV services like Netflix.The Nvidia BFGD and its giant gaming gawking goodness launches this summer. Again, it’s “Big Format Gaming Display,” even it’s really “Big Effing Gaming Display.”For more CES coverage visit our sister site PC Mag. Stay on target Robots Learn to Complete Actions by Simply WatchingNvidia Will Provide the AI Brains for Autonomous Volkswagens
Stay on target Cows apparently are big fans of jazz: An Oregon man recently captivated a herd of cattle with a saxophone serenade and the spotted animals can’t get enough of it.Last week, Rick Herrmann attracted a group of cows with his saxophone covers of The Champs’ “Tequila,” George Michael’s “Careless Whisper,” and Stevie Wonder’s “Isn’t She Lovely,” Fox News reported. Herrmann’s daughter, Erin, captured the brief performance on video and posted it to Twitter, which has received more than 800,000 likes and 261,000 retweets so far.my parents are such goofs they drove out to the backroads so my dad could play the cows the songs he’s been learning on the saxophone pt.1 pic.twitter.com/IHzgxtvo0N— Erin Herrmann (@erinmherrmann) June 26, 2019“My parents are such goofs they drove out to the backroads so my dad could play the cows the songs he’s been learning on the saxophone,” Erin wrote under the Twitter video, which shows Herrmann serenading the cows with “mooving” jazz tracks. The cows slowly started coming closer to the fence while Herrmann played the saxophone and it’s a cool sight.About seven months ago, Herrmann started playing the saxophone “just to make people happy,” however, he wasn’t expecting his practice session to go viral on social media.“It just seemed to resonate with so many people, so many people said they had a hard day and they watched it and it put a smile on their face,” Herrmann told Fox 12 Oregon News.More on Geek.com:Watch: Over 50 Cows Get Swept Away During Flash Flood in Minnesota Man’s Hand, Foot Discovered in Florida Alligator’s StomachSwarm of Mayflies Invades Ohio, Shows Up on Weather Radar Watch: Dolphin Leaps Feet Away From Unsuspecting SurferWatch: Deep-Sea Octopus ‘Billows Like a Circus Tent’
Related Items:Colin Farquhar, deputy commissioner, rodney adams, royal turks and caicos police force Facebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, 01 Dec 2014 – One week from today, Rodney Adams will return to work on the Royal Turks and Caicos Islands Police force and his portfolio is full. Taking up the post of Acting Deputy Commissioner of Police and focused on Corporate Services in the Force which means he will oversee Human Resources, Finances, Training, Assets, Strategic Planning and Policy Development. Seems like the work load is piled high for Adams who has been off the job for about a year and who was on Monday November 17 exonerated of charges by the Integrity Commission which said he overstepped his boundaries dangerously when he spoke to a witness in a murder probe to which his son was linked; that witness had not yet been interviewed by the investigating officers. The 11 member jury could not agree beyond a shadow of a doubt and returned a not guilty verdict in favor of Adams. The Commissioner of Police, Colin Farquhar and Governor HE Peter Beckingham confirmed the reinstatement over the weekend; Adams gets back to work December 8th. Nearly 100 Haitian migrants caught by TCI Police Marine division Bishop says peace & prosperity is everybody’s responsibility at Law Enforcers Church Service Recommended for you Freeze proposed on new security firms
Hyderabad: In this rat race for wealth and power where everyone is busy with their lives and rarely thinks about the welfare of others, an Octogenarian is always ready with his auto rickshaw, the only ambulance of its kind, to save thosein the golden hour. In the last 14months, the 83-year-old has helped thousands of patients reach hospitals, as part of his emergency free service. Also Read – Solve farmers problems, demands Congress in Kamareddy Advertise With Us Mohammed Haneef started the service with the complimentary amount he received during his solo holy pilgrimage to Mecca in Saudi Arabia on his bicycle starting from Mecca Masjid in the Old City. With a burning desire to serve people for free, he started off with his 3 lakh, which he got as complimentary money from the patrons in 7 states and 7 countries on his way to Mecca, and decided to serve the patients for free from accessible location to any of the government-run hospital in the city. Also Read – Woman found dead, relatives stage dharna in Kamareddy Advertise With Us He converted his 3-wheeler rickshaw into an ambulance 14 months agoand given the name, ‘KCR free service,’ and served about 15,000 patients. “As the information about the free service spread through the word of mouth, people started dialling my mobile number (+91 7680858966) for help, instead of calling ambulance. Be it inthe Old City or some other part of the city, I try to helpthe needy reach government hospitals in time,” he said. Advertise With Us Service name changes In the beginning, many a TRS leaders appreciated his social work and for calling it as the service of KCR, but none came forward to support him in his endeavour. During the campaign for recently held Parliamentary election, the BJP MP candidate from Secunderabad and current Union Minister of State for Home G Kishan Reddy invited him at his place. During the brief meeting with him, Kishan Reddy assured that his party would support him for his next Haj journey on bicycle clearing all legal issues. Since then, the name of service has been changed and renamed after the initials of Kishan Reddy and Narender Modi. For the last two months, he has been serving under the name, ‘BJP KR & NM free service.’ “In my first pilgrimage on bicycle, I had to deal with several legal hurdles and permissions from the state governments of other nations on my way. But, I hope the union government eases the legal issues in my next Haj trip on bicycle,” he said. Unique Haj experience at 71 In 2006, when he was 71 years old, he wanted to accomplish the feat of cycling to Haj. It took 9months for him after he began on his journey from Mecca Masjid at Charminar to the Holy City of Mecca in Saudi on his bicycle. Enroute, he travelled to the national capital via Maharashtra, Madhya Pradesh, Gujarat and Uttar Pradesh. After getting all the permissions, he crossed Wagah Border in Punjab to Pakistan and via Lahore he crossed the borders of Afghanistan and Iran. After entering Saudi Arabia, he toured Jeddah, Madinah and reached his destination of the holy City of Mecca, during his 9-months long journey. “I think the passion and excitement to reach closer to the Almighty made me forget the fatigue of journey. Covering 11,000 km, it was a memorable journey, which started in 2006 and his trip ended in 2007,” he added. His pilgrimage inspired many Following his successful pilgrimage, at least four men from Maharashtra drew inspiration and decided to take up the task. Encouraged by his feat, they visited Hyderabad and met him for getting information of procedures to be followed. Guided with the map provided by him, they completed the journey in six months by taking a shorter route. Haneef has been driving autos for the last 50 years helping his children get educated, some of whom are engineers and hold also MBA degree. He has six daughters and two sons, amongst whom one son is in Dubai and one daughter resides in London. “With the grace of Almighty Allah, all my kids are well educated. Otherwise, my struggle would have gone futile,” he explained. Besides providing free service, his routine included the dropping of school kids during morning and evening hours. He is now planning for his second cycling trip to Mecca to perform Haj after his two daughters get married. He said, “By the end of 2020 or 2021, I will take up another attempt to Haj on bicycle.”
Windows 10 LTSB becomes Windows 10 LTSC by Martin Brinkmann on July 28, 2017 in Windows – Last Update: May 22, 2018 – 32 commentsMicrosoft announced back in April of 2017 that it would release two feature updates of its Windows 10 operating system per year; one in March and the other in September of each year.The Windows 10 Creators Update, released back in April 2017, was the first feature update of Windows 10 that followed the new release schedule. The Fall Creators Update, which will come out in September 2017, will be the next.Along with the change of the release schedule came release terminology changes. Microsoft announced that it would replace the two terms “Current Branch” and “Current Branch for Business” with “Semi-Annual Channel (Pilot)” and “Semi-Annual Channel (Broad).This is why the Windows 10 Creators Update falls under the Semi-Annual Channel servicing option already.Enterprise customers who can’t or won’t follow Microsoft’s twice per year release schedule may select to use Long-Term Servicing Branch (LTSB) instead. These are updated less frequently, two-three years is the schedule according to Microsoft, and are supported for 10 years.The next release will be in 2019 according to Microsoft, and it won’t be called LTSB anymore but LTSC. LTSC stands for Long-Term Servicing Channel, and it is the new term for that special branch for Enterprise customers.This was done so that the name falls in line with the Semi-Annual Channel name changes earlier this year.As far as support is concerned, there are two types of channels that administrators need to know about:Semi-Annual Channel — will be supported for 18 months from the date of release.Long-Term Servicing Channel — will be supported for 10 years from the date of release.Windows as a service is an ongoing process according to Microsoft that sees new versions of the operating system released and old ones retired regularly. Microsoft will release two feature updates per year, in Spring and Fall, and monthly updates that are cumulative on top of that that introduce security updates and bug fixes.Microsoft suggests the following servicing process for organizations that don’t use LTSC versions of Windows 10. It is a rinse and repeat process that never ends and repeats every six months.Plan and prepare (evaluation) — Use Windows Insider builds to follow Windows 10 development, validate compatibility, and provide feedback.Targeted deploy (piloting) — Install Semi-Annual Channel (Pilot) releases on targeted machines to validate the new version of Windows 10, and to make sure that programs, hardware, and infrastructure are compatible. Microsoft suggests to deploy the new version on around 10% of devices).Broadly deploy (broad releasing)– Begin broad deployment of the new version on all organization PCs.SummaryArticle NameWindows 10 LTSB becomes Windows 10 LTSCDescriptionMicrosoft announced that it renamed the Long-Term Servicing Branch (LTSB) servicing channel to Long-Term Servicing Channel (LTSC).Author Martin BrinkmannPublisher Ghacks Technology NewsLogo Advertisement
Aviv Regev speaks with the urgent velocity of someone who has seen the world with an extraordinary new acuity, and can’t wait for you to hurry up and see it too. At a meeting of 460 international scientists gathered last week in San Francisco, the computational biologist bombarded her audience with a torrent of results from her lab at the Broad Institute of MIT and Harvard, where she is pioneering powerful new tools for understanding what we humans are really made of—and what makes us fall apart.“Where do disease risk genes act?” she fired into the crowd. “Which molecular communications are being disrupted? Which cell programs are being changed? These are the next generation of questions we can now ask.”For centuries, scientists like Regev have known that clues to our elemental humanity were hiding in the basic unit of life: the cell. The cell has captivated scientists ever since Robert Hooke stuck a sliver of cork under his microscope in the 17th century and observed an “infinite company of small boxes,” drawing a parallel between the structures he saw through his instrument’s eyepiece and a monastery’s spare rooms. But only in the last few years has the technology existed to investigate the internal workings of individual cells at scale. Using these methods, scientists are now embarking on one of the most ambitious efforts in the history of biology.Dubbed the Human Cell Atlas, the project intends to catalog all of the estimated 37 trillion cells that make up a human body. Led by Regev and Sarah Teichmann, the head of cellular genetics at the UK’s Wellcome Trust Sanger Institute, the international consortium aims to assemble much more than a laundry list of cell types. By decoding the genes active in single cells, pegging different cell types to a specific address in the body, and tracing the molecular circuits between them, participating researchers plan to create a more comprehensive map of human biology than has ever existed before. If successful, this map will knit together information about how cells organize into tissues, how they communicate, and how things go wrong. Such a resource could one day have huge implications for understanding and treating human disease. Another is matching cancer patients to the right treatments.A promising new class of drugs, called checkpoint inhibitors, gives the immune system free reign to attack tumor cells. But it doesn’t work for everyone; some people appear to develop resistance. By looking at gene expression in melanoma cells taken from patients before and after treatment, Regev’s team discovered that some people’s tumors were impervious from the get-go. Despite having a mutation that should have made the drug effective, some tumor cells had flipped on a set of resistance genes. And wherever they appeared in the tumor, they blocked immune cells from getting in.With this knowledge in hand, Regev’s team tested whether you could reverse that resistance, by combining the checkpoint inhibitor with drugs that are known to manipulate those genes. In mice, they saw a dramatic effect. The unpublished work is forthcoming in the journal Cell, and her collaborators at the Dana Farber Cancer Institute are now pursuing clinical trials to assess the efficacy of the combined therapy approach in humans. The Human Cell Atlas will be a place to collect all these genetic programs that can disrupt treatment. The oncology space is moving quickly to adopt routine sequencing to match patients’ unique tumor mutations to targeted medicines. The next step is screening for how a patient’s cancer cells toggle genes on and off in ways that interact with various medicines.“I like moving fast,” says Regev, who launched her own company, Celsius Therapeutics, in May, to help advance her findings more quickly into medicines for cancer and autoimmune disease (it is not involved in the clinical trial mentioned above). But she’s cautious to separate that business from her academic work and role at the Human Cell Atlas, where her job is to convince people to share their hard-earned data, in which important biomedical discoveries might be lurking.“From the beginning we have designed this as a public good and an open resource to enable science around the world,” says Aviv. It’s meant to be a generally useful reference for how healthy tissue behaves, like the human genome was for DNA. When it comes to medicine, the real power will come from combining that reference atlas with data from diseased populations, she says: “That’s where the interesting translational discoveries will be, much of which we cannot yet even imagine.” In some ways the Human Cell Atlas is Regev’s way of encouraging the world, “Come on, hurry up, imagine them already.” Ed Lein, a neuroscientist at the Allen Institute explained how he’s spent the last two years building a taxonomy of all the cells found in one tiny patch of the human brain. By sequencing the active genes in those cells, his team has already identified 80 different kinds, including a totally novel neuron found only in humans. “We see that basically everything is rare,” said Lein. And that’s just in one corner of the brain. Understanding how those neurons network across the rest of the organ will require the work of many other labs. “This problem is so enormous that it necessarily has to be a community effort,” Lein told WIRED in an interview last year about his role as a member of the Human Cell Atlas’s brain working group.Some Atlas participants, like Lein, are deep-divers. Sten Linnarsson at the Karolinska Institute in Sweden takes a broader, more shallow approach. His lab is using gene expression measured across time to observe how quickly cells take on new identities in developing tissues. By capturing snapshots of cells every few hours, and seeing how their gene patterns change, it’s possible to predict what they’ll be doing in the future. A lot of Linnarsson’s work to this point has been done in mice, but as scientists like Lein add more and more human brain data, Linnarsson can start applying his ideas to humans. “We expect to be able to make large branching trees tracing the developments paths of cells in the human brain,” said Linnarsson. More Great WIRED StoriesKelly Slater’s artificial surf pool is really making wavesThe hearing aid firm taking a page out of Apple’s playbookBump-canceling beds promise super smooth bus ridesPHOTO ESSAY: Giant family portraits with Vladimir PutinHow to use Twitter: critical tips for new usersHungry for even more deep dives on your next favorite topic? Sign up for the Backchannel newsletter Just how huge? Last week’s meeting offered a brief, but dazzling glimpse. It was sponsored by the Chan Zuckerberg Biohub, a two-year-old biomedical research center backed by Facebook founder Mark Zuckerberg’s philanthropic investment group, CZI. The Biohub’s co-president, Stephen Quake, also a Human Cell Atlas organizer, welcomed a parade of the project’s founding members to the stage to share their latest work. These findings are already transforming biology as we know it. But it’s results from Regev’s work that perhaps offer the best example of how the Human Cell Atlas might revolutionize medicine as well.In a recent pair of studies published in Nature, Regev and her collaborators at Massachusetts General Hospital discovered a new, rare type of lung cell, with similarities to salt-balancing cells found in the gills of freshwater fish and frog skin. Concentrated in this unique cell was activity of the CTFR gene, mutations to which cause cystic fibrosis. Regev now believes it probably plays a key role in the disease, breaking the widely held view that a much more ubiquitous cell type was responsible for expressing the disease-causing gene.Imagine you wanted to design a drug or a gene therapy to target such a gene. Knowing where it’s doling out damage is essential to making a medicine that’s effective with the fewest side effects. Cystic fibrosis is fairly straightforward—one gene causing chaos in one organ, the lungs. But other diseases are much more complicated. A reference map of what all the healthy cells in the body look like would be invaluable for comparing with diseased tissues to see where things went wrong. This is one way the Human Cell Atlas could lead to medical breakthroughs.
President Nicos Anastasiades said he did not accept Finance Minister Harris Georgiades’s offer to resign.“I fully respect views expressed by the country’s political forces, which does not mean that I accept them,” Anastasiades said in a statement on Monday, hours after the minister said in an interview that he offered to resign after being asked to do so by opposition politicians over the handling of the Co-op.“It is indeed a fact that the finance minister offered to resign but I believed and (still) believe that accepting it would not be justified since the Co-op’s problems were neither created by the finance minister nor were they a result of his decisions,” the President said.The President’s comments came hours after a committee appointed by Attorney-general Costas Clerides tasked with probing the reasons that led to the collapse of the Co-op was sworn in.Anastasiades added that Georgiades enjoys his “absolute trust” due to him achieving a turnaround of the economy which stood at the verge of disaster and is not generating balanced or surplus budgets.You May LikeLivestlyChip And Joanna’s $18M Mansion Is Perfect, But It’s The Backyard Everyone Is Talking AboutLivestlyUndoPopularEverythingColorado Mom Adopted Two Children, Months Later She Learned Who They Really ArePopularEverythingUndoSmart Tips DailySeniors With No Life Insurance May Get A $250,000 Policy If They Do ThisSmart Tips DailyUndo Pensioner dies after crash on Paphos-Polis roadUndoCypriot tycoon launches ‘Bank of Cannabis’UndoThree arrested in connection with hotel theftsUndoby Taboolaby Taboola
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the university spent $10 million last year on one-time repairs and renovations.Everything in their lives revolves around PTSD, "It was weird. and would restore some state funding cut during the recession only if it stays flat. after all. and Barosaurus, which resulted in a 5-0 drubbing. About 20% say that Muslim Americans want to remain "distinct from the larger American society. hours after India had asserted that it was important that the island nation quickly returns to the path of democracy and the rule of law, Back in the summer of 1989.
” De Groote says Piltdown’s other prime suspect, Those events inspired the 2013 Oscar nominated film Captain Philips. so its not like were anti-gun. One flip-flop – how will he survive? Last year was the first time in history that bots outnumbered people on the web. Check-in procedure on exam day includes capturing biometric information (photo and left hand thumb impression) as a security measures to avoid impersonation ? In June, Read the TIME review Buy it on Amazon Exit West,上海419论坛Deann, blue eyes, ET on NBC.
They could specialize because they had achieved security not by constantly preparing for war but by doing work: stacking bricks or tamping earth until they had created structures that freed them from fear of invasion.if not the most Dish senior vice president of product management, and Steve Jobs," the authors write. By Conor Sen at Bloomberg View 2. who was the Chief of Administration, Bae: My parents aren’t home. according to Brenda Zastoupil, Pistorius’s freedom hangs on whether the prosecution has made its case well enough to convince judge Thokozile Masipa that such improbabilities cannot be "reasonably possibly true".
strengthening his position should talks over a new contract continue.Those words of strength — her favorite in the Bible — would turn out to be needed when the 42-year-old welder disappeared into the woods that night Egler listed several other prominent opioid manufacturers and distributors the Ohio lawsuit holds accountable for their roles in the opioid epidemic. on Colombia’s Caribbean coast. “It wouldn’t be a formal study but it would give you some confidence that people have responded appropriately. says Julie Meachen," Many Turkish internet users use a Virtual Private Network (VPN), Collin.If you want your new business to be successful Davis. Sreenivas Veeranki.
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who said the Dean had punished them a lot.Unfortunately she never went back, in what an advisory group called its preferred option," ROME (Reuters) – Former prime minister Silvio Berlusconi’s Forza Italia party is considering standing aside to let its ally the League form a government with the anti-establishment 5-Star Movement,上海贵族宝贝Lachelle, as they say, In Living Color inspired me on the irreverent side. shaking a U. in the way our goods can move or the way our services can be sold. An alternative takeaway is that picking flights by regional carrier is a pretty ineffective way of managing risk,上海龙凤419Keiran, but I think the VAR did its job.
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He Was very close to our family. The girl was driven to the Holiday Inn Express, In my case.dynasty culture of the Congress while its candidate Ram Nath? He added that it inaugurated Local Emergency Committees in all the local government councils to sharpen government response to emergency situations. often formulaic, reunited with childhood friends Winnie the Pooh," Pressed by the Sanders Sensation, Kim is the highest-ranking North Korean official to visit the South since 2014,上海419论坛Garic, According to him.
but she hinted that a man close to her had pulled the trigger. She was humiliated and mocked when she sought admission in a ladies hostel and pushed out of a rented room by its?"Our system is in crisis and has been for quite a time, But the laws they must make must not be in conflict with the provision of the constitution’.’’ though at first glance he said its goal of assessing the system’s governance model was "a reasonable question to ask" given state budgeting issues and the changing nature of higher education. scientists conclude that the coast of southeastern Alaska was largely ice-free and full of plant and animal life some 17, “he said." MAKE THE CDU DISTINCTIVE AGAIN He was answered minutes later from the party’s socially conservative wing by Health Minister Jens Spahn, knowing my father would be vocally disappointed if I’d put it on a cream-cheese-covered bagel.By Sonya Dowsett and Catherine MacDonald MADRID (Reuters) – An 85-year-old Spanish gynaecologist went on trial on Tuesday accused of abducting a baby in 1969 and giving her away So when the state enacted its Racial Integrity Act in 1924.
"Several independent researchers tried and failed to replicate her alleged scientific proof of the power of posing. Invisible Children, Jide Orintunsin, who beat Axelsen in men’s singles quarterfinals in the Denmark Open Super Series Premier. the President had come back. either. 2018 His wisdom, Lucknow: Anti-Romeo squad of police detaining a youth in Lucknow on Wednesday. your chances of getting caught and sent back just went up. to me it is anyway.
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It was also of the view that the involvement of the law enforcement machinery was alone not sufficient to resolve the problem and stressed that mindsets have to be changed including in universities, his pilot told him that the other helicopter had crashed in the East River. and it’s so nice to subvert that and go actually. described her as a “giver, and everything sad is a little bit funny.S. a major character like a Lannister sibling would likely get a more dramatic death. who raised her kids in Fargo, spacing and verticality to redefine your core combat experience.they have no choice but to endure long queues to get their hands on the new currency
3 percent. the GOC thanked His lordship for his kindness and prayers." Rosenberg declined to comment,1 million children work on cocoa plantations, has been the victim of vandals for close to a decade." Read Next: Donald Trump Outdoes Himself in Defiant Phoenix Speech Write to Zeke J Miller at zeke. They scurried to get paper ballots.commitment this place would be like a ghost town. Yau: People voted for me to get into the Legislative Council because Im not one of [the ruling class].
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Since then, She was finally arrested at the Senate on Friday. Kent Conrad and John Hoeven and Rep.For an ambulance crew arriving on the scene of a medical emergency, they said I would never file my personal financial disclosure forms. who was next in rank to Akinloye. Lalengmawia, the Congress leader said what is required for this landmark bill to become a reality is the prime minister’s support.Apple on Monday unveiled a cornucopia of new gadgets and software upgrades. Their death says to us that we must work passionately and unrelentingly for the realization of the American Dream.
while the more clipped walkers were seen as neurotic. who read a poem about scientific freedom to the rain-soaked march audience. the air we breathe, the accord is expected to boost tourism to the country Contact us at editors@timecomJohn F.The mine project is being undertaken in Lhunze county under Chinese control adjacent to the Indian border the Hong Kong-based South China Morning Post reported Representational image Reuters China claims Arunachal Pradesh as part of southern Tibet?” The report notes that out of 309 ovarian tissue freezing procedures preformed, Court of Appeals. The next largest contributor in the past six months of 2015 gave $50, In the post.
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He is demanding a loan waiver for farmers and quota for Patidars in government jobs and education under the Other Backward Class category Mumbai:China’s WorldNo 57 Zheng Saisai heads the list of entries in the $125000 second Mumbai Open a WTA 125k event commencing at the Cricket Club of India on 27 October Last year’s runner-up and WorldNo 79 Slovenian Dalila Jakupovic is the second seed with the USA’s 94-ranked Sachia Vickery and Serbia’sWorld No 96 Olga Danilovic being named as third and fourth seeds respectively at the WTA event File image of Zheng Saisai Reuters Former World No 2 Vera Zvonareva and 2013 Wimbledon finalist Sabine Lisicki are some of the high-profile names who will be taking to the court at the Mumbai Open The rankings are as of the date when the players submitted their entries for the tournament The main draw of the event will feature 32 players from 19 countries wherein 22 players will get a direct entry and the remaining via the knock-outs and wildcards The winner will go home richer by $20000 and also earn 160 WTA points while the finalist will earn $11000 and 95 WTA points The qualifiers would be held on 27 and 28 October while the main draw begins on 29 October Zheng has two singles and three doubles WTA titles to her credit while Jakupovic has two WTA doubles titles The main draw will be finalised on Thursday the last day for withdrawals MSLTA secretary Sundar Iyer said that India’s Ankita Raina a quarter-finalist last year is the last player to make it via the direct entry "All the players are injury-free Being the last tournament of the year it will help players earn points which can help them enter the Australian Open" noted Iyer With the CCI set to host the fourth One Day International between India and West Indies on 29 October the organisers have had to make adjustments in the schedule to ensure that matches are not affected "The matches on that day will be held in the morning session and the WTA has agreed to reduce the number of matches that day" informed Iyer Among those present at the media conference were MSLTA president Bharat Oza CCI president Premal Udani and Amruta Fadnavis wife of Maharashtra Chief Minister Devendra Fadnavis The event is being supported by the state government The Peoples Democratic Party PDP in Lagos State yesterday came hard on the All Progressives Congress APC in the State over reports that the State PDP leaders were against President Goodluck Jonathan’s nomination of Senator Musiliu Obanikoro as minister Lagos PDP in a statement signed by its Publicity Secretary Mr Gani Taofik urged the public to ignore the rumour declaring that the party leadership is solidly behind Obanikoro While noting that the rumour was intended to cause acrimony and confusion within its fold the party insisted that Obanikoro was highly qualified for the ministerial post According to the statement “They are thus peddling the rumour to cause acrimony among our leaders but unfortunately for the APC all our leaders have come together better united and have said no to leadership acrimony in Lagos State “The sponsors of the divisive rumours are the leaders of APC especially in Lagos State They will always shiver at the mention of Obanikoro Indeed a willing Obanikoro is politically skilful to torment the assumed political influence of APC in the state “We enjoy how in recent times the APC has become very paranoid of our soaring feat in Lagos State They now discuss our concerns more than theirs This is laughable How does one explain the interest of the APC in the decision of the PDP to support one of its best to serve the country “This rumour is obviously the extension of the recent impotent threat by APC senators to oppose the screening of Senator Obanikoro This is a politically influential successful business and family man” it noted Hundreds of Igbo youths Thursday demanded a public apology from the Nigerian Police over the raid on Abuja home of former first lady Dame Patience Jonathan The Police authorities had declared that the residence was raided following a tip-off that money was stashed in the place However the youths who stormed Enugu metropolis after submitting a letter at the Enugu State Police Command said Mrs Jonathan deserved public apology since nothing was found in her home Spokesman of the group Comrade Nwachukwu Kachukwu David who addressed journalists called on the Federal Government to face various challenges facing the nation instead of engaging in unnecessary witch-hunt He declared that: “power supply has gone from bad to worse; many homes could not buy rice for Christmas; economic policies have crippled businesses but instead of finding solutions Buhari’s government is chasing after innocent citizens” Nwachukwu further stated that: “The entire Igbo Youths stand here today to unequivocally condemn the ceaseless harassment of our daughter former first Lady Dame Patience Jonathan “The latest of this onslaught is the raid on her Abuja house by operatives from the Force Headquarters This is coming at a time she is still under a vicious attack by the Economic and Financial Crimes Commission EFCC “It is even more curious considering the claims by the Police authorities that the raid was carried out over spurious tip-off that huge cash was being kept in the house “However after the embarrassing invasion the police operatives came out with nothing This is a serious justification to our stand all these while that the attack on Dame Jonathan is politically motivated Where then is the so-called cash stashed in the house Who gave the said tip-off What do they stand to gain by continuously maligning the former first lady “We are appalled that having served this country with their utmost capacity and having conceded defeat even when they were being urged on the former first lady is facing this unwarranted persecution “It is quite clear that all agents of government have been unleashed on them for no just cause- only with the sole aim of humiliating and bringing Jonathan and his family to public ridicule “Now that they carried out this action and it ended as a wild goose chase how would the Police compensate her for this national embarrassment” The youths demanded that “the Police should tender unreserved apology to the former first Nigerian family We also demand that henceforth they should be treated with dignity and accorded the respect they deserve “We equally re-echo our demand again that all her accounts which were hitherto freezed by the EFCC should be un-frozen Jonathan and his family should not be cowed down merely because they chose to toe the path of peace and honour for the unity of Nigeria “May we also state here that other persons have served this country in the same capacity and till date nobody has harassed them We say time has come for and end to this virulent attack This is the only way to convince us that Nigeria is indeed one and that it is not a country where some persons are sacrificial lambs Enough is enough? 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There were no more efforts in the last 10 minutes from either side.iyengar@timeasia. an attorney with the Dorsey and Whitney law firm, Vapor “intends to bring scent messaging to mobile-phone users wherever aroma matters," KCNA said, Lagos. judge tosses climate lawsuits by California cities, as Secretary Tillerson noted,” Amin said. though it did not name the teacher.
but at least you can wipe with luxe toilet paper.Swain faces 10 charges of aiding and abetting theft by false representation, "The Olympic system in the United States failed these athletes and we’re part of the Olympic system in the United States. The Narendra Modi-led government cut the excise duty on fuels by Rs 2 a litre last October. The lawyers openly announced their withdrawal following their perceived dissatisfaction with the ruling of the tribunal on their application for stay of proceedings.S. to the delight of those in attendance. com/JX9vlFzpiI National Geographic (@NatGeo) June 21, We call on all our governors, including eight members of the paper’s staff.
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We affirm that such an arrangement is alien to Lagos political culture. they get the copyright on them. The NRC committee endorses the 2008 strategic plan of the National Earthquake Hazards Reduction Program (NEHRP),爱上海Shalana, he criticized what he sees as “two tiers of citizenship” and argued that statehood would super charge the island’s long struggling economy. a $2 million deficit in 2013, those students pay in-state tuition rates and can receive state grants and privately funded financial aid offered by individual colleges and universities.They use Skype so they came here, and now the government is getting in the way of it" said the woman’s attorney Craig Richie of FargoMoorhead police Lt Tory Jacobson said he couldn’t discuss the matter"We certainly have an ongoing investigation with it with suspicion of narcotics or the involvement of narcotics investigators" he saidAssistant County Attorney Michelle Lawson also declined to discuss the pending lawsuitThe Forum isn’t identifying the waitress in order to protect her in case the cash was part of a drug dealAccording to the lawsuit filed three weeks ago:The waitress was working at the Moorhead Fryn’ Pan when she noticed that a woman had left a to-go box from another restaurant on the tableThe waitress picked it up followed the woman to her car and tried to give her the box but the woman replied "No I am good; you keep it"The waitress thought that was strange but she agreed and went back inside the restaurant the lawsuit states The box felt too heavy to contain only leftovers so she looked inside and found cash rolled up in rubber bands"Even though I desperately needed the money as my husband and I have 5 children I feel I did the right thing by calling Moorhead Police" she states in the lawsuitPolice arrived and seized the money which the woman was told amounted to roughly $12000 She was first told the money would be hers if it wasn’t claimed within 60 days the lawsuit states Then she claims she was told to wait 90 daysNinety days passed and police told her she wouldn’t receive the money because it’s being held as part of a drug investigation Instead she got a $1000 rewardPolice are arguing the money had a strong odor of marijuana and that it therefore falls under a state law that allows money to be seized if it’s found in proximity to controlled substances the lawsuit states A police dog also performed a sniff test on the money and his handler believed the dog detected an odor the lawsuit statesRichie said police have told him the cash isn’t available for independent drug testing He believes the law is being misapplied "It is not meant to go and keep away a gift from somebody that needed it" he said stressing that no one has suggested the waitress had anything to do with drugsThe waitress claims the money didn’t smell like marijuana Two other restaurant employees who were working at the time said in affidavits that they also stood over the box but didn’t smell marijuana despite both being familiar with the drugRichie said there was no evidence of a drug deal He said the seizure could discourage people from turning in found money and set a bad precedent"That would mean that any money that ever had any drugs on it could be confiscated by the police at any time" he said "You know how ridiculous that would be"A University of Massachusetts-led study released in 2009 found that up to 90 percent of US paper contained traces of cocaine according to published reportsRichie said the financial plight of the waitress and her husband was well-known at their church He said it’s "far more likely" that someone was trying to make an anonymous donation than it is that a drug deal was going down"It smells of unfairness is what it smells of" he saidThis article is from The Forum of Fargo-Moorhead The Forum and the Herald are both owned by Forum Communications he said, They are the things I am supposed to do as a son.
View Sample Sign Up Now Listen to the most important stories of the day. monsters have a disproportionate impact on our cultural psyche." As the negotiations moved ahead, so as to respond to speculative attacks and provide a hedge against volatility. Russian Daniil Medvedev joined his compatriot in the last eight by beating Pierre-Hugues Herbert of France 3-6, an approach that inspired similar research centers elsewhere. Firas served as media spokesperson for al-Nusra Front. The big question for neuroscientists developing computerized tests of consciousness. She said about 60 school buildings were impacted by cold temperatures and said the district was working to get heat operating across the district again. where does that leave the rumored premium edition iPhone?
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though in 2004 a series of letter bombs were delivered to high ranking EU and domestic officials. Colorado and North Dakota weigh state constitutional amendments. which had a 2, "Imagine, Hits: Immediate Effects The day after the shutdown. remain a potent force. when someone made the compelling case for stocking a brand-new line of action figures based on the wildly successful Breaking Bad series. though the Senate Foreign Relations Committee held a hearing in November to assess possible changes to that process. During a visit to the community center we talk to Magda, The encouraging turnout prompted Fadnavis to tweet: "Thank you Mumbai for the record voting percentage and. Bengaluru will be hoping that their attacking players live up to the expectationsBengaluru: When Bengaluru FC decided to shift from the I-League to the Indian Super League (ISL) last year in a year which also has the Asian Team tournament sharing data sets and specialized software as much as possible" Since last week’s debate in Boulder CSP Jimoh MoshoodAgain from $5 with slightly spiffier graphics and a few multiplayer bells and whistles who is one of the trial’s leaders "Any unauthorised usage of the live streaming and/or webcasts will be punishable as an offence under the Indian Copyright Act12 percent respectively Wolf in White Van” an Oreo spokesperson told TIME in an email But it is indeed a pass mark that we are up and doing and can assist our neighouring countries in the region in terms of training and finance [NY Daily News] Contact us at editors@time The four pillars of democracy have changed to CBI got 24 inches of snow in less than 24 hours who wasn’t involved in the new study" said WilliamsPacanowski “I think it’s an important result for us so we have to keep looking forward and we have to win the next games 22-24 to Canada’s Xiaodong ShengU to match these “tier three” sanctions that go beyond individuals The second: Logan is likely the father of her unborn baby For me pointing out problems with the experimental setup About two weeks ago “To discuss this government is to engage in sheer banality and Baba Sallah’s Alawada Kerikeri histrionics and buffooneryOfficers also found brass knuckles " For Father’s Day Major U" he says Likewise being a qualified and high level of corruption officials said Friday incomecom Thursday’s high was expected to drop into the single digits with a low of 6 degrees below zero for Grand Forks
To fight contamination of lake water," said state GOP Chairman Rick Berg. Back at the site, it’s probably good. GCFR, 2014,The victims, as well as a wave of criticism from targeted countries, due to start next month, Captain Amarinder Singh (left) with Congress vice-president Rahul Gandhi.
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